A Study Has Linked Ibruprofen To Male Infertility, But Don't Freak Out

Frederick Owens
January 10, 2018

Their trial on 31 healthy men who volunteered for the study found that a 1,200mg-a-day dose of ibuprofen induced compensated hypogonadism within 14 days. Of course, there is a bright side to this new finding, and that is to limit your intake of ibuprofen. Unfortunately, a new study says that ibuprofen can actually reduce fertility rates in men.

While it is important to note that this was a small study and more research is clearly called for, the fact that ibuprofen is so widely and casually used by so many men makes it a point of concern, particularly for those who intend to start a family.

The study isn't the first to suggest that ibuprofen could be causing more harm than good.

Infertility in men can be caused by a variety of factors including trauma, genetic and hormonal disorders, age, weight, smoking, drug and alcohol use, and environmental toxins. In addition to producing sperm, testicles secrete testosterone, the primary male hormone. Each dose was 600mg, equivalent to three over-the-counter pills.

The research, which was published in the Proceedings of the National Academy of Sciences journal, showed that the men who took the high doses of ibuprofen developed the disorder known as compensated hypogonadism.

Before you go raid your medicine cabinet, Advil and Motrin are two brand names for ibuprofen.

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Professor Allan Pacey from the University of Sheffield, cautions: "The results suggest that long-term use (several weeks) of ibuprofen can affect the production of the male hormone by the testicles". This condition, CNN explains, can lead not only to fertility issues - it can also be linked to depression, fatigue, and possibly even a higher risk of heart problems.

The safety and efficacy of active ingredients in these products has been well documented and supported by decades of scientific study and real-world use.
Professional athletes, however, do tend to take ibuprofen frequently, so this research could spark a serious look into the way those under physical strain treat their aches and pains.

Such a condition is the result of the body increasing testosterone production because the testes stop producing adequate levels of it.

In the subjects, the condition was temporary, but study leads told the Guardian it could become a permanent problem in cases of long term overuse.

"Long-term use of ibuprofen has other negative effects on overall health so people should only be taking it over a period of weeks, months or years if a doctor has prescribed it".

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